This function generates a matrix of metacells where each metacell corresponds to a CNV cluster.
The CNV matrix is calculated by chromosome arm. If specified, certain clusters will be labeled as "Benign"
rather than "Clone".
Usage
generateCNVClonesMatrix(seuratObj, healthyClusters = NULL)
Arguments
- seuratObj
A Seurat object containing CNV data and metadata.
- healthyClusters
A numeric vector or NULL
. If provided, clusters specified in this vector
will be labeled as "Benign" instead of "Clone". Default is NULL
.
Value
A matrix of CNVs with row names corresponding to the clone or benign labels and columns representing
the chromosome arms.